Molecular basis of Barrett's oesophagus and oesophageal adenocarcinoma

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review of barrett’s oesophagus to oesophageal adenocarcinoma: new prospect

today’s knowledge on oesophageal adenocarcinoma and its rising incidence has encouraged researcher to illustrate relationship between barrett’s disease and progression to adenocarcinoma. the incidence of this disease has been accelerated sharply in current decades since people life has changed. studies have been demonstrated that several potential factors including genetical  and environmental ...

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Review of Barrett’s Oesophagus to Oesophageal Adenocarcinoma: New Prospect

physiological changes in epithelial form and function(1). It was a pre-malignant disease of oesophageal adenocarcinoma (OA) in which normal oesophageal epithelia were replaced by columnar epithelia at gastro-oesophgeal junction(2-8). The increasing incidence of BO and OA over the last two decades shows that it was becoming a major public health concern in developed countries such as the US, UK ...

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Duodenal juice stimulates oesophageal stem cells to induce Barrett's oesophagus and oesophageal adenocarcinoma in rats.

the present study was performed to examine the sequential process of the development of Barrett's oesophagus (BE) and oesophageal adenocarcinoma (ADC) induced by duodeno-oesophageal reflux (DER) in rats. Total gastrectomy was performed in male Wistar rats weighing approximately 250 g followed by reconstruction with oesophago-jejunostomy, which causes unavoidable DER without exposure to exogenou...

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Barrett's oesophagus and adenocarcinoma

Address: 1Registrar UK National Barrett's Oesophagus Registry (UKBOR), and Honorary Senior Lecturer, University Department of Surgery, Royal Free Hospital, Rowland Hill Street, London NW3 2PF, UK, 2Joint director UK National Barrett's Oesophagus Registry (UKBOR), and visiting Professor, University Department of Surgery, Royal Free Hospital, Rowland Hill Street, London NW3 2PF, UK, 3MRC Cancer C...

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Demographic and phenotypic features of 70 families segregating Barrett's oesophagus and oesophageal adenocarcinoma.

BACKGROUND Based on reported familial patterns, inheritance of a predisposition of developing Barrett's oesesophagus (BO) and oesophageal adenocarcinoma (OAC) likely follows an autosomal dominant model of most inherited cancer syndromes. oesophagus (BO) and oesophageal adenocarcinoma (OAC) likely follows an autosomal dominant model of most inherited cancer syndromes. AIMS We analysed the phen...

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ژورنال

عنوان ژورنال: Gut

سال: 2006

ISSN: 0017-5749

DOI: 10.1136/gut.2005.089144